Detecting neurodegeneration (ND) biomarkers in plasma is challenging due to their low abundance.

Our Neuro IP Kit enables easy enrichment of the neurodegeneration-relevant proteins total Tau, different phospho-Tau´s (p50, p181, p217, p231), brain-derived Tau, beta-Amyloid (Aβ), total α-Synuclein, and patho-oligomeric α-Synuclein from plasma by immunoprecipitation. As a positive side effect, all non-specific matrix effects that can interfere with downstream analysis are eliminated. After enrichment, a detection system of choice can be applied (BD Tau LUM ELISA, BD Tau-217 LUM ELISA, SIMOA, Lumipulse, ELECSYS, MSD, ELISA).